Strongest Numbing Cream: In-Depth Analysis and Opinions

We have researched 13 numbing creams for you.

When it comes to managing pain, having the right topical solution can make a significant difference. Numbing creams offer a convenient and effective way to alleviate discomfort, whether it's for minor skin procedures, tattoo applications, or even deep muscle aches.

Our comprehensive list is dedicated to those who seek the ultimate in pain relief. We have researched and compiled the best options on the market to soothe your pain worries away. Each cream has been evaluated for its potency, ingredient quality, and user feedback to ensure you get the relief you need when you need it the most.
To simplify the price comparison, we determine the prices for the individual articles on Amazon, Ebay and other shops and link the offers via partner links where applicable. This means that we receive a commission if you buy something that we recommend - the price does not change for you.

What to Look for in Strongest Numbing Creams

Important criteria

  • Maximum strength lidocaine or other active anesthetic components
  • FDA approval
  • Non-oily composition
  • Fast-acting formula
  • Long-lasting effect
  • Suitable for your specific use (e.g., tattooing, medical procedures, cosmetic use)

1.) Active Ingredients

When selecting the strongest numbing cream, check the active ingredients, as they are responsible for the numbing effect. Look for Lidocaine, Tetracaine, Benzocaine, or a combination thereof. The concentration of these ingredients is crucial – typically, Lidocaine concentration can range from 2% to 5% for over-the-counter creams, but the strongest may require a prescription. Be wary of maximum dosage and application area size to avoid systemic toxicity, especially with high concentration products.

2.) Intended Use and Onset Time

Consider the intended use of the numbing cream to ensure it suits your specific needs. Different creams are formulated for various procedures, from tattoos and piercings to medical procedures like injections. Additionally, the onset time, which is the time it takes for the numbing effect to kick in, varies among products. Choose one that aligns with the duration of the procedure you want to use it for, keeping in mind that some creams require application well in advance.

3.) Manufacturer Credibility and Reviews

Research the manufacturer to ensure credibility and safety standards. Look for companies with a good track record, necessary certifications, and compliance with health regulations. User reviews and ratings can provide insights into effectiveness and any potential side effects. Avoid creams with a high volume of negative feedback, as they may not be effective or could cause adverse reactions.

4.) Side Effects and Allergies

Be aware of potential side effects, such as redness, swelling, or allergic reactions. If you have sensitive skin or a history of allergic reactions, opt for a numbing cream with a formula suitable for sensitive skin. Conducting a patch test before the full application can help identify any adverse reactions. Always read the label for a list of potential allergens and heed any warnings provided.

The Strongest Numbing Creams of our Choice

Our Pick
Curist 5% Lidocaine Cream Maximum Strength
Curist 5% Lidocaine Cream Maximum Strength
Size: 6 Ounce (Pack of 1)
  • Lidocaine 5% pain cream for deep relief
  • Made in the USA with tested ingredients
  • Numbing cream for pain relief and soothing
  • Extra large 5% lidocaine tube for bulk use
  • Curist pain relief cream stronger than others
$ 22.99 *
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2
beaueli Tattoo Numbing Cream(50g)
beaueli Tattoo Numbing Cream(50g)
  • Fast-Acting & Long-Lasting pain relief
  • Reduces tattoo swelling for up to 6 hours
  • Allows continuous tattoo session without interruptions
  • Comfortable & relaxed tattooing experience
  • Desensitizes skin effectively for pain-free experience
  • Contains healing Aloe Vera for tattoo recovery
  • Suitable for various cosmetic procedures like tattooing
  • Safe for all skin types, vegan, and cruelty-free
$ 17.99 *
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3
Zensa Numbing Cream
Zensa Numbing Cream
Type/Color: Numbing Cream Size: 1.05 Ounce (Pack of 1)
  • Maximum strength 5% lidocaine cream
  • Does not change skin texture or affect color
  • Long-lasting pain relief for 2 to 4 hours
  • Fast-acting, starts working in 20 minutes
  • Ideal for tattoos, cosmetic, and medical uses
  • Water-based, non-oily formulation
  • Loved by 50,000+ artists and healthcare professionals
  • Preferred choice of top professionals
  • Hypoallergenic and cruelty-free
  • Made in the U.S.A.
  • Safe to use on open skin and sensitive areas
  • Suitable for all skin types and children
$ 43.99 *
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4
Adellina Tattoo Numbing Cream (50g/1.7oz)
Adellina Tattoo Numbing Cream (50g/1.7oz)
  • Powerful numbing action for tattoo relief.
  • Formula includes Purslane for skin healing.
  • Lasts up to 6 hours for entire tattoo procedure.
  • Multipurpose cream for various cosmetic needs.
  • Easy to use with clear instructions for application.
$ 23.95 *
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5
Treatonic Deep Numbing Cream (50g/1.7oz)
Treatonic Deep Numbing Cream (50g/1.7oz)
Type/Color: White
  • Deep numbness for piercing, waxing, tattooing, and more.
  • Effective healing with Arnica and Emu Oil.
  • Multipurpose for tattooing, piercing, waxing, and more.
  • Odor-free, oil-free, and non-greasy formula.
  • Easy to apply and safe for all skin types.
$ 19.85 *
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6
BlackCobraSupply 8 Hour Maximum Strength Lidocaine
BlackCobraSupply 8 Hour Maximum Strength Lidocaine
Type/Color: black
  • Numbing cream for microneedling with deep numbing.
  • Long-lasting effect of 5% lidocaine for 8 hours.
  • Easy application with quick skin absorption.
  • Suitable for all skin types, including sensitive skin.
  • Trusted brand in the tattoo industry.
$ 24.99 *
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7
Nupharmisto Lidocaine Tattoo Numbing Cream :
Nupharmisto Lidocaine Tattoo Numbing Cream :
Type/Color: White
$ 17.90 *
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8
Ebanel 5% Lidocaine Numbing Cream
Ebanel 5% Lidocaine Numbing Cream
Model: Numb520 Size: 1.35 Ounce (Pack of 1)
  • FSA HSA Approved Eligible OTC Medications & Treatments
  • Topical lidocaine numb cream relieves pain, burning, itching
  • Reduces inflammation and soreness in local and anorectal areas
  • 5% Lidocaine Cream Maximum Strength provides immediate pain relief
  • Works for minor aches, cuts, scrapes, burns, and irritations
  • Provides relief from mosquito, bug, and insect bites
  • Treats postpartum relief, hemorrhoid shrinking treatment, and anorectal disorders
  • Enhanced Liposomal Deep Penetrating Skin Numbing Cream
  • Fast-acting & long-lasting, starts numbing in 3-5 minutes
  • Peaks after 20-25 minutes and lasts 1 hour
  • Numbing performance may vary based on skin thickness and metabolism
  • Oil-Free, Odor-Free & Non-Greasy, hypoallergenic and non-addictive
  • Water-based formula for easy application and removal
  • Made in USA in an FDA Registered Facility
  • Cruelty-Free, cGMP Certified, child-resistant cap
  • Performance test before treatment highly recommended
$ 17.69 *
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9
WELMATE 5% Lidocaine
WELMATE 5% Lidocaine
Size: 5.5 Ounce (Pack of 1)
  • Supports aches, pains, itching, soreness, burning.
  • Helps with anorectal discomfort and insect bites.
  • Can be used after getting a tattoo or piercing.
  • Fast-acting: numbing starts in 2-3 minutes.
  • Long-lasting: lasts up to an hour.
  • Contains 5% Lidocaine, the strongest OTC formulation.
  • Enriched with Vitamin E to aid swelling.
  • Moisturizes and hydrates skin, reducing irritation.
  • Child-resistant packaging and cruelty-free.
  • Vegan friendly with no harsh chemicals.
$ 22.95 *
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10
Acolye Tattoo Numbing Cream Extra Strength
Acolye Tattoo Numbing Cream Extra Strength
Model: AC-120 Type/Color: White Size: 1.7 Ounce (Pack of 1)
  • Lasts up to 6 hours for long-lasting results
  • Enhanced healing properties for faster recovery
  • Multipurpose numbing cream for various cosmetic procedures
  • Easy to use with simple application instructions
  • Satisfaction guaranteed with 60-day money-back guarantee
$ 24.98 *
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11
SNTE Tattoo Numbing Cream
SNTE Tattoo Numbing Cream
Type/Color: Bright green Size: 2.12 Fl Oz (Pack of 1)
  • Numbing effect lasts 6-8 hours.
  • Allows finishing tattoo session in one step.
  • No need to ask tattooist to stop or slow down.
  • Real relaxation during tattoo process.
  • Suitable for all skin types.
  • Made with natural ingredients.
  • Non-greasy and easy to clean.
  • Soothes and protects skin from irritation.
  • Menthol ingredient promotes faster healing.
  • Multipurpose numbing cream.
  • Relieves tattoo, piercing, hair removal, and more.
  • Extra large capacity.
  • Simple and safe to use.
  • Caution for patch testing before use.
  • External use only.
$ 19.99 *
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12
UberScientific Uber Numb 5% Lidocaine Topical
UberScientific Uber Numb 5% Lidocaine Topical
Size: 2 Ounce (Pack of 1)
  • 5% topical lidocaine cream provides maximum strength relief
  • Temporarily relieves pain, itching, soreness, and burning
  • Reduces swelling and protects irritated skin
  • Fast-acting numbing gel cream begins working in minutes
  • Numbing effect peaks after 20-25 minutes
  • Effectiveness lasts for 1 hour from peak
  • Extra soothing and hydrating with vitamin E and Allantoin
  • Soothes and protects skin from irritations
  • Suitable for minor cuts, scrapes, burns, insect bites
  • Water-based and odor-free with no harsh chemicals
  • Non-greasy and easy to apply and remove
  • Made in the USA with high-quality standards
  • Secured with a child-resistant cap
  • Never tested on animals - cruelty-free
  • Manufactured under cGMP certification
  • Hypoallergenic and non-addictive
  • Performance test prior to treatment is recommended
$ 17.69 *
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13
Mad Rabbit Painless Tattoo Numbing Cream Maximum Strength
Mad Rabbit Painless Tattoo Numbing Cream Maximum Strength
Type/Color: White Size: 1.5 Ounce (Pack of 1)
  • Clean & effective ingredients for tattoo relief.
  • Fast-acting pain relief with 5% Lidocaine.
  • Numbs targeted areas within 3-5 minutes.
  • Peak effectiveness after 25-30 minutes.
  • Lasts for roughly 1 hour.
  • Fragrance-free & non-greasy formulation.
  • Doctor formulated and lightweight for easy application.
  • No-mess removal.
  • Instructions: apply to clean, dry skin.
  • Massage until fully absorbed.
  • Apply 45 minutes - 1 hour before tattoo appointment.
  • Wash hands immediately after application.
  • For extra concentration, use plastic wrap.
  • Partner with Mad Rabbit Soothing Gel and Tattoo Balm for post-tattoo relief.
$ 24.99 *
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* All prices incl. VAT, plus shipping if applicable. Prices, delivery times and costs may change in the meantime. The selection of products was made independently of the manufacturer and without any claim to completeness. All links to products are external partner links through which we may receive compensation. All information without guarantee.

Top Numbing Creams for Every Buyer

Professionals
For experts seeking reliable numbing creams for client procedures, explore a curated selection. These creams are favored by industry professionals for their performance.
Tattoo Enthusiasts
Discover numbing creams that are popular in the tattoo community. They provide comfort during long tattoo sessions without compromising the art's quality.
Home Use
Find top-rated numbing creams that are suitable for various home treatments. Ease into your personal care routines with products that offer the desired numbing effect.
Medical Patients
Patients undergoing medical procedures can find solace in highly-rated numbing creams. These selections are geared towards minimizing discomfort during medical applications.

Questions You Might Ask

Numbing creams are topical anesthetics used to temporarily numb the surface of the skin. They are commonly used to reduce pain or discomfort caused by needle injections, tattooing, body piercing, waxing, and minor surgical procedures.
When choosing a numbing cream, consider the concentration of the active ingredient (usually lidocaine), the onset time of the cream, how long it lasts, ease of application, skin type compatibility, and whether it's approved by the Food and Drug Administration (FDA) for the intended use.
To apply numbing cream, first clean and pat dry the area where you will apply it. Spread a generous layer of cream over the skin without rubbing it in. Cover the area with a plastic wrap to enhance absorption, and wait for the specified amount of time indicated on the product instructions before commencing your procedure.
If you have sensitive skin, look for numbing creams designed for sensitive skin types. Always perform a patch test before full application to ensure there is no allergic reaction. Consult with a healthcare professional if you are concerned about using numbing creams on sensitive skin.
Possible side effects of using numbing creams include redness, itching, or a slight burning sensation at the application site. More serious but rare side effects could include an allergic reaction, uneven heartbeats, dizziness, or difficulty breathing. If you experience these serious side effects, seek medical attention immediately.

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How to Choose the Strongest Numbing Cream

Struggling with pain and looking for a solution that doesn't involve popping pills? Numbing cream might just be the ticket. It’s a topical anesthetic that can dull the pain in a specific area of your body without systemic effects. In this guide, we'll explore what you need to know to pick the strongest numbing cream that suits your needs perfectly, whether you're prepping for a tattoo session, a medical procedure, or just want to ease a painful spot.

Understanding Numbing Cream Components

The power of numbing cream lies in its active ingredients. The most common are lidocaine, benzocaine, prilocaine, and tetracaine – either used alone or in combination. Lidocaine is a widely preferred choice for its effectiveness and minimal side effects. However, the strength and formulation of these components vary across products.
It's crucial to understand the concentrations. Over-the-counter options generally contain up to 5% lidocaine, which is suitable for minor procedures. But stronger formulations are available through prescriptions. It's essential to follow the dosage instructions carefully – more isn't always better and can lead to adverse effects.
Some creams may also include vasoconstrictors like epinephrine to reduce bleeding and prolong the numbing effect. This is especially useful for procedures like tattooing. However, those with certain health conditions should be cautious, as vasoconstrictors can affect heart rate and blood pressure.

Evaluate Your Pain Threshold and Purpose

When shopping for the strongest numbing cream, consider your own pain threshold and the purpose of application. For instance, if you're gearing up for a lengthy tattoo session, look for a cream with long-lasting effects. On the other hand, a lower concentration might suffice for a quick blood draw or small cosmetic procedure.
Your skin type can also influence the cream's effectiveness. Thicker skin, like on the soles of your feet, may require a stronger formulation as opposed to more sensitive areas. Don't forget to account for any skin conditions or allergies, which could be exacerbated by certain ingredients.
It's also important to consider the procedural requirements. Some medical and beauty procedures may have specific instructions regarding the use of numbing creams. Always consult with a professional to ensure that you're using a cream that's effective and safe for your specific situation.

Application Tips for Maximum Efficacy

To leverage the full strength of your numbing cream, proper application is key. Start with clean, dry skin to ensure optimal absorption. Apply the cream generously, following the manufacturer’s instructions for amount and timing before the pain-inducing procedure begins.
Covering the cream with plastic wrap can enhance its effectiveness by increasing absorption and heat, which helps the numbing agent penetrate the skin more deeply. Just be sure to set a timer — leaving numbing creams on for too long can be dangerous.
Last but not least, give the numbing cream enough time to work its magic. Some creams might take up to an hour to fully numb the skin, so patience is a virtue. And remember, once the area is numb, avoid putting pressure on it to prevent unknowingly causing injury.

Safety Considerations and Side Effects

Safety should never be an afterthought when dealing with the strongest numbing creams. Be aware of potential side effects, such as redness, swelling, and allergic reactions. Test the cream on a small skin area before full application to avoid a major adverse reaction.
Under no circumstance should numbing cream be applied to broken or irritated skin, as it can enter the bloodstream and lead to toxicity. If you do experience adverse effects or symptoms like dizziness, difficulty breathing, or an irregular heartbeat, seek medical attention immediately.
Always store numbing creams according to the manufacturer’s instructions and out of reach of children. And remember, numbing cream is for external use only – never ingest it, and avoid applying near your eyes or mouth unless directed by a health professional.

Making an Informed Decision

Before making a purchase, do your research. Read product reviews, seek recommendations from professionals, and consider brands with a reputable track record. The price might be a factor, but the cheapest option isn't always the best when it comes to effectiveness and safety.
Additionally, verify the cream's expiration date upon purchase – an expired product might not only be less effective but also puts you at risk for skin irritation. Once you have all the information, you'll be empowered to make a decision that ensures comfort and eases your pain without compromising safety.

Hands-on Reviews and Recommendations from Discussion-Boards

In the quest to identify the most potent numbing cream, considerable research has been conducted, resulting in the identification of valuable resources for those interested in this topic. Our selection process has been meticulous, favoring content notable for its credibility and helpfulness. As such, we have compiled a comprehensive list of the top links that cover various aspects of the strongest numbing creams on the market. These have been organized into four distinct categories for ease of navigation: detailed product reviews, insightful forum posts, engaging Reddit discussions, and informative video content.
May 2, 2019 — Topical Pain Relievers​​ Pain relievers in cream or patch form—OTC or prescription—may cause fewer side effects than pills because less of the...
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Aug 23, 2021 — “Higher doses of ibuprofen and acetaminophen may be appropriate for more complex and traumatic oral surgical procedures, such as extraction of...
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Jun 13, 2021 — These creams, gels, and lotions can be very effective, says Gil Yosipovitch, MD, professor of dermatology and Stiefel chair of medical ...
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Apr 27, 2020 — Kosharskyy also recommends keeping diclofenac gel (1%) and lidocaine patches (4 %) on-hand for topical pain relief when the pain site is intense.
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I've used vasocaine spray on clients and had some success with it. thing is, skin has to be broken before it works. So it's great for that last...
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The strongest lidocaine cream I could find online is only 10% lidocaine, and I have it. It's effectiveness isn't all that great.
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I use Bactine from a foaming soap dispenser. I find it sits on the skin better and my clients notice a big difference. It doesn't last super...
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1. Ebanel 5% Lidocaine Numbing Cream · 2. Numb520 Topical Anesthetic Lidocaine Cream · 3. Inked Inspired Topical Anesthetic Cream · 4. Zensa...
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I use toochi tattoo numbing cream and keeps me numb for about 10 hours. Its way better than the chemist ones, and my artist sells it at...
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Top 10 Best Tattoo Numbing Cream (2023) - YouTube
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Links to the Best Tattoo Numbing Cream we listed in today's Tattoo Numbing Creams Review video & Buying Guide: 1.

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